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Skip to content Dept. Immunobiology   Professor Koetsu OGASAWARA, DDS, PhD Assistant Professor Kazuki WATANABE The Department of Immunobiology focuses primarily on Natural Killer (NK) cells, which are critical for both innate and adaptive immunity. These cells play an important role in the elimination of virally infected cells and tumors. NK cell functions are regulated by the opposing signals from activating or inhibitory receptors, and our laboratory has been focusing on activating and inhibiting receptors on NK cells and T-cells. Recently, we found that NKG2D, an activating receptor, is important for viral immunity, tumor immunity and the development of autoimmune diabetes. Therefore, we will explore the molecular mechanisms underlying recognition of NK cells and T-cells against target cells in viral immunity, tumor immunity, autoimmunity and allergy. Thus, our laboratory mainly focuses on three areas of research, namely: Tumor Immunology, Autoimmune Diseases and Metal Allergy. Research Topics: • Tumor Immunology • Autoimmune Diseases • Metal Allergy   About Us IDAC’s Mission Statement Greeting &＃038; Mission Notable Alumni History of IDAC IDAC&＃8217;s Affiliations News &＃038; Events Research Facilities &＃038; Faculty Research Facilities Common Facilities Resources &＃038; Equipment Brain Imaging Cell Center Equipment Admission &＃038; Courses Mechanisms of Aging Overcoming Intractable Cancers Overcoming Age-Related Brain Diseases Achieving &＃8220;Smart-Aging&＃8221; Public Relations &＃038; Info. Office Maps &＃038; Directions Give to IDAC Contact Us Privacy Policy &＃038; Disclaimer IDAC COVID-19 Update Navi About Us IDAC’s Mission Statement Greeting &＃038; Mission Notable Alumni History of IDAC IDAC&＃8217;s Affiliations News &＃038; Events Research Facilities &＃038; Faculty Research Facilities Common Facilities Resources &＃038; Equipment Brain Imaging Cell Center Equipment Admission &＃038; Courses Mechanisms of Aging Overcoming Intractable Cancers Overcoming Age-Related Brain Diseases Achieving &＃8220;Smart-Aging&＃8221; Public Relations &＃038; Info. Office Maps &＃038; Directions Give to IDAC Contact Us Privacy Policy &＃038; Disclaimer IDAC COVID-19 Update Navi ©Institute of Development, Aging and Cancer, Tohoku University